Coherence tomography versus fluorescence angiography with related macula degeneration (2007)

Evaluation of optical coherence tomography in the diagnosis of age related macula degeneration compared with fluorescence angiography – HTA report

The aim of this HTA report is to investigate the efficacy and efficiency of OCT compared to FA. Ethical, societal and legal aspects are also considered. A systematic literature search was performed in 34 international databases which yielded 2324 articles. Eight publications were included for assessment, according to predefined selection criteria. Future studies have to show whether OCT may give diagnostic information essential for therapeutic decisions in addition to FA and whether it can replace FA in selected cases. The number of patients included in these studies should be high enough to answer relevant questions with sufficient statistical power. An economic model calcula-tion can be built upon the resulting findings.

The report may be obtained for free at http://www.dimdi.de (abstract and summary in English).

ISSN: 1861-8863